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Disclosed herein is a method for the treatment or prevention of overweight, optionally in the presence of at least one weight-related comorbidity

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Abbreviations AST: Aspartate transaminase ALT: Alanine transaminase UA: Uric acid TP: Total protein AL: Albumin AY: Amylase FR: Ferritin C: Cortisol -HB: Beta-hydroxybutyric acid Ht: Hematocrit CVD: Cardiovascular disease GRF: Glomerular filtration rate BW: Body weight BH: Body height BF: Body fat FFM: Fat free mass TBW: Total body water BMI: Body mass index BSA: Body surface area References Ezpeleta, M

During aging, ECM interactions become disrupted due to the fragmentation of collagen fibrils