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AOD9604 and Energy Balance Research In obese ob/ob and lean C57BL/6J mice treated for 14 days via mini-osmotic pumps, AOD9604 significantly reduced body weight gain in obese mice, associated with increased in vivo fat oxidation and increased plasma glycerol levels as an index of enhanced lipolysis without the hyperglycaemia or reduced insulin secretion associated with intact hGH treatment

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Next, due to the poor bioavailability, permeability, and instability of both carnosine and quercetin 48 , their topical applications are limited

It is vital for protecting mitochondria, the energy centers of the cell