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Distinct functions for Wnt/-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis

Retatrutide produced 28.7% average weight loss at 12mg in 68 weeks, compared to 20.9% for tirzepatide at 15mg in 72 weeks

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While we provide functional context for several loci identified in this study, including TUT4 , RYK , MOXD1 , UBAP2 , GATA5 , and others, we acknowledge that many of these interpretations rely on indirect evidence from related biological pathways or associations with non-ocular traits such as age-related macular degeneration, cardiovascular traits, or metabolic phenotypes