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doi: 10.1016/j.cca.2022.09.018 87 TomlinsonJ

TB-500s defining and best-characterized action, by contrast, is exactly that: sequestration of monomeric G-actin through the LKKTETQ actin-binding motif, which regulates the cytoskeleton that drives cell migration

FOXO4-DRI is also known as Proxofim (research designation), FOXO4 D-Retro-Inverso peptide (full descriptive name), Forkhead box O4 (DRI) (gene-derived name), and FOX04-DRI (alternative spelling)

Patients who already have exceptionally high pyridoxine levels or signs of pyridoxine toxicity (such as sensory neuropathy) should not continue to receive high-dose supplementation until those symptoms resolve