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Treatments include dietary interventions to enhance iron intake from iron-rich foods and oral iron supplementation, despite potential gastrointestinal side effects ( 2.2 Iron overload in the brain In contrast to iron deficiency, excess iron in the brain is neurotoxic due to its ability to produce reactive oxygen species (ROS) and resultant oxidative stress (Salvador et al., 2010)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 178.Matsumura N, Aoyama K

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