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18H04794), the Naito Foundation, a research grant from the Princess Takamatsu Cancer Research Fund 15-24728, the Uehara Memorial Foundation, and Japan Agency for Medical Research and Development (JP19gm5010002)

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Analysis of CSF biomarkers revealed that IL-6 and GFAP levels increased from baseline to post-treatment, coinciding with a trending decrease in cytokines and chemokines associated with senescence

Leaf senescence: correlated with increased levels of membrane permeability and lipid peroxidation and decreased levels of superoxide dismutase and catalase