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An alternative possibility involving S-2,4-dinitrophenylation of thiols or other cellular nucleophiles was excluded based on the lack of an equal effect of CDNB, which could produce a similar arylation without release of NO

Dihexa mimics HGF and activates the c-Met receptor directly

But its effects on the central nervous system, particularly on neurotransmitter systems implicated in depression, deserve serious attention from researchers exploring mood disorder interventions