The results demonstrated that subclinical hypothyroid patients treated with selenomethionine showed positive effects, which were further enhanced by co-therapy with myo-inositol, likely due to the presence of autoantibodies (TPOAb and TgAb) [43]
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In APP/PS1 mice, BBB permeability and pericyte number are reduced, and -amyloid induces mitochondrial autophagy-dependent ferroptosis via the CD36/PINK/PARKIN pathway, resulting in blood-brain barrier damage and contributing to AD