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Optimization of Sulforaphane bioavailability from a glucoraphanin-rich broccoli seed extract in a model of dynamic gastric digestion and absorption by Caco-2 cell monolayers

Bacteria in the digestive tract get hold of the carnitine we eat and convert it into trimethylamine-N-oxide (TMAO), and it is high levels of TMAO that appear to do the dirty work, enabling cholesterol to burrow into artery walls and build up plaque

It is important to note that this neurohormonal stress response has an additional endocrine leg in the form of glucagon: together, one of the important effects of this trio is to enhance the release of glucose, amino acids and fatty acids, a coordinated catabolic response to stress (186)