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Over four draws from a 10mg vial, this can mean losing 0.04 to 0.2ml of solution, enough to reduce your final dose by 5 to 10%

Frontiers in Bioengineering and Biotechnology, 9

Exclusion criteria included the following: (1) alcohol consumption greater than 20 g/day

About Japan Early-stage Trial of Ultrahigh-Dose Methylcobalamin for ALS (JETALS) The Japan Early-stage Trial of Ultrahigh-Dose Methylcobalamin for ALS (JETALS) is an investigator-initiated study conducted as a multicenter, placebo-controlled, double-blind, randomized Phase III clinical trial to verify the efficacy and safety of high-dose methylcobalamin (mecobalamin) in patients with amyotrophic lateral sclerosis (ALS)