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Zoloft (sertraline) is primarily used to treat mental health conditions, including: Depression (Major Depressive Disorder) Anxiety disorders (Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder) Obsessive-Compulsive Disorder (OCD) Post-Traumatic Stress Disorder (PTSD) Premenstrual Dysphoric Disorder (PMDD) Social Anxiety Disorder Zoloft Mechanism of Action Generic Name: Sertaline Zoloft is a selective serotonin reuptake inhibitor (SSRI)

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