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Tobacco Health Risks The tobacco component introduces several health concerns: Nicotine addiction develops quickly, even with occasional spliff use Respiratory irritation tobacco smoke is more irritating than cannabis smoke alone Cardiovascular effects nicotine increases heart rate and blood pressure Cancer risk tobacco contains numerous carcinogenic compounds Reduced lung function combination smoking may compound respiratory impacts Medical Patient Considerations Medical cannabis patients should carefully weigh spliff use against their treatment goals

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An additional feature of e-cigarettes that is now often manipulated is nicotine type, based on the ratio of the R- and S-nicotine isomers: synthetic nicotine contains a mixture of both R- and S-nicotine, whereas traditional tobacco-derived nicotine contains primarily S-nicotine 15

The band also played many songs from their most recent album, Everything Is Going To Be Alright, like The Forest and In Heaven