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In summary, these limitations, predominantly cross-sectional and self-reported study designs, absence of long-term longitudinal research, minimal mechanistic investigation in youths, and sparse data on exercise outcomes, constrain our current understanding of how e-cigarette use may affect adolescent pulmonary function and physical activity

The longetivity of the fragrance needs some attention aswell

The heart rate should fall How much does heart rate increase when smoking

Fearing a new generation will become addicted to nicotine and that the pouches could be a gateway to smoking, the taskforce is calling for strict regulation of the products