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Organoids were seeded as 50-l domes (~10,000 cells per dome) and maintained in lung organoid medium (Supplementary Table 1)

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Clinical contacts with unmotivated patients should emphasize the rewards and relevance of quitting, as well as the risks of smoking and anticipated barriers to abstinence

Public Health Service Clinical Practice Guideline for Treating Tobacco Use and Dependence, in that it advocates delivery of tailored behavioral counseling interventions in conjunction with pharmacotherapy