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Step 4: Material Replacement (When Necessary) Sometimes, smoke damage is too extensive for cleaning alone

And it wasnt until more recently, when the Brazilian government created more strict bans on smoking in public places and monitored sales of cigarettes to minors, that the trends of smoking finally started to slowdown in Brazil

IQOS heats tobacco instead of burning it, significantly reducing the amount of smoke and chemicals released

Intake information included self-report of estimated date of HIV diagnosis, nadir CD4+ cell count (for participants where laboratory values were unavailable), list of ARTs, and AIDS status (based on conditions that determine this diagnosis)