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For instance, individuals with certain genetic variations may metabolize nicotine more rapidly, which can lead to differences in smoking behaviors and levels of addiction

Damage to the lungs and a decline in lung function are directly proportional to the number of packs of cigarettes smoked per day multiplied by the number of years smoked, a metric known as pack years. The longer years in the pack, the more probable the lungs may be permanently damaged

"Commission Delegated Directive (EU) 2022/2100 of 29 June 2022 amending Directive 2014/40/EU of the European Parliament and of the Council as regards the withdrawal of certain exemptions in respect of heated tobacco products (Text with EEA relevance)"

The potency of marijuana has quadrupled since the mid-90s