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If the user is exposed to higher amounts of nicotine compared to cigarettes, then tolerance and dependence to nicotine will occur faster

The new regulation only allows smoking in outdoor spaces, and prohibits smoking where food, drinks, or social and leisure activities take place, the area should be 10 meters away from the smoke-free spaces and completely isolated with no passage or access to other places

Moreover, as in smokers with or without chronic obstructive pulmonary disease (COPD), low bone mineral density and muscle mass are associated with a lower diffusion capacity and probably with emphysema 11