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The concept of tobacco harm reduction, defined by the US Institute of Medicine (IOM) as "decreasing total morbidity and mortality, without completely eliminating tobacco and nicotine use" (Institute of Medicine2001), is being considered by some regulators

Smoking can lead to cancer in multiple parts of the body, including the bladder, blood, cervix, colon, rectum, esophagus, kidney, stomach and more

Compared with HC, nicotine-dependent e-cigs users showed increased ReHo in the right rolandic operculum and the right insula ( p 0.05, FDR corrected)

1 2 3 "Prenatal Substance Abuse: Short- and Long-term Effects on the Exposed Fetus"