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Historical and physical clues for suspecting such conditions include papyraceous/hemosiderotic scars, molluscoid pseudotumors, subcutaneous spheroids, markedly visible subcutaneous vessels, triangular face with sunken eyes, early-onset cutis laxa and premature ageing, bifid uvula/cleft soft palate, hypertelorism, dolichocephaly, vascular complications, history of osteochondritis dissecans, and sudden death in close relatives

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Consequently, the administration of these tests typically aligns with the principles outlined in the Fourth Amendment

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