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Taking certain medications, especially taking (or abruptly stopping) monoamine oxidase inhibitors (MAOIs), (medications used to treat depression or Parkinson's disease, bulimia, and anorexia nervosa), linezolid, intravenous methylene blue, antiepileptic drugs or Wellbutrin

Vaping, Smoking, Dipping & Chewing Tobacco Cause Reflux At-A-Glance Nicotine has adverse effects on many different organs in the body, and it specifically causes pharmacological relaxation of the lower esophageal sphincter, leading to acid reflux and Barretts esophagus