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Although there is evidence that bupropion and its metabolites affect noradrenergic transmission, bupropion also acts upon many other brain systems

Multiple nodule scenarios: When coding R91.8 for multiple nodules, some payers may require specific documentation about which nodule is being followed or whether all are being monitored

Biomarkers of exposure and potential harm, relevant to both combustible cigarette exposure and smoking-related diseases, are useful in the assessment of potential changes in health effects resulting from switching to alternative non-combustible nicotine-containing products