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This case report delineates the temporal response of plasma clozapine concentrations and dose-corrected clozapine plasma concentrations in a 33-year-old inpatient with schizophrenia who had a substantial smoking history and ceased smoking abruptly during dose titration

The harmful components of cigarette smoke exacerbate mitochondrial oxidative stress, which is believed to contribute to the aggravation of CP caused by smoking 23