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The Teflon Toxin: DuPont and the Chemistry of Deception

The share of Americans who smoke has fallen dramatically since 1970, from nearly 40 percent to about 19 percent

Compared with traditional meta-analysis using linear mixed effect models, MR-BRT relaxes the assumption of a log(linear) relationship between exposure and risk, incorporates between-study heterogeneity into the uncertainty of risk estimates, handles estimates reported across different exposure categories, automatically identifies and trims outliers, and systematically tests and adjusts for bias due to study designs and characteristics

Shadel noted that most of the studies on IQOS have been conducted by Philip Morris, and much more research is needed by independent researchers who are not associated with the company to determine the safety of the product