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One of the proteins produced from the polyprotein is P3N-PIPO, which is a fusion protein of the N-terminal end of P3 (component of viral replication complexes) and a translation frameshift product derived from a hidden pipo cistron (Tennant et al., 2018)

The useabusedependence hierarchy in Section I.C.5.b.2 barely applies to F17 with only a dependence stem, there is no abuse/use code to outrank

The dangers of smoking are well-documented, from the increased risk of cancer and heart disease to the negative impact on the environment