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Millions of preventable deaths Despite campaigns aimed at the reduction of tobacco smoking, it is still a very common practice and is considered the primary cause of preventable mortality globally, claiming 8 million lives annually [2]

Pressurized metered-dose inhaler (beta-agonists, corticosteroids, cromolyn sodium, anticholinergics) The optimal technique for these devices is actuation during a slow (30 liters/minute or 3 to 5 seconds) deep inhalation, followed by a 10-second breath hold

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