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Another study ( n = 3,216) analyzing maternal cotinine levels during pregnancy and ones risk for ADHD found that maternal active smoking (cotinine level 11.49 ng/mL) during pregnancy was significantly associated with an increased risk of total difficulties (OR = 1.67) while maternal low- and high-passive smoking (cotinine level 0.220.51 ng/mL and 0.5211.48 ng/mL respectively) increased the risk (OR = 1.11, 1.25, respectively) but was not statistically significant [67]

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