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Supplementary Material Abbreviations Used %RSD percent relative standard deviation ACN acetonitrile CBD cannabidiol DAD diode array detection DEA Drug Enforcement Agency DNPH 2,4-dinitrophenylhydrazine EDDS electronic drug-delivery systems FDA Food & Drug Administration HCI Health Canada Intense HPHC harmful and potentially harmful constituent HPLC high performance liquid chromatography LLOD lower limit of detection LLOQ lower limit of quantification m slope QC quality control R 2 coefficient of determination SCSM-STEP single cigarette smoking machine SD standard deviation S y standard deviation of the response THC 9 -tetrahydrocannabinol THF tetrahydrofuran Author Disclosure Statement J.O.E

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Table of Contents 10 Smart Ways to Brighten Teeth Stained by Smoking or Meds 1