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Forty-two experimental animals (Wister rats) were involved and they were divided into groups A (control), group B (test group 1), C (test group 2) and D (test group 3)

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Centrilobular (Centriacinar) Most common Affects upper lobes Strongly associated with smoking 2

"The law is clear that, before marketing tobacco products for reduced risk, companies must demonstrate with scientific evidence that their specific product does in fact pose less risk or is less harmful." The agency fired off a warning letter to JUUL Labs in September 2019 saying it was illegal for the company to claim its JUUL e-cigarettes were safer than smoking tobacco