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Besides being involved in the pathophysiology of several types of malignant neoplasms, not only in the lungs, smoking represents the first cause of chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD) [5, 6], as well as a major determinant of cardiovascular (CV) diseases, such as myocardial infarction, stroke and peripheral arterial diseases

"The first words I will say," he had told me, as we drove to the function, "will be: Are there any other rich bastards in this room? At which point I will raise my arm and you must raise yours too

The variant provides enough satisfaction to prevent the frustration that sometimes accompanies switching to much lighter options