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Efficacy Data: Response rate: Not reported Remission rate: Not reported MADRS change: -12.8 (S47445) vs -8.5 (placebo) at 6 weeks (Phase 2) Time to response: 2-4 weeks Source Why it might interest you: Different mechanism (AMPA modulation), potentially fewer side effects (notably less sexual dysfunction and weight gain), and faster onset than standard antidepressants

And as an actor, I think all actors will agree, no one gives a more honest, natural, truer performance than Harry Dean Stanton." Lynch also directed Stanton in Wild at Heart and The Straight Story

Or at least, thats what folks thought