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Parodied in the log-sawing scene in Ren and Stimpy Adult Cartoon Party : the scene itself is as sex-like as it goes, but Ren's post-sawing smoke caps it all

PDF file Schick S, Glantz S Philip Morris toxicological experiments with fresh sidestream smoke: more toxic than mainstream smoke Tobacco Control 2005

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Activated epithelial cells and innate immune cells also release pro-remodelling factors, such as epidermal growth factor receptor (EGFR) ligands, and transforming growth factor (TGF)- , which trigger goblet cell hyperplasia, EMT, fibroblast activation, and airway smooth muscle cell proliferation and hypertrophy ( 5.1 Epithelial structural changes in asthma Asthmatic airways show increased numbers of basal cells with an impaired proliferation and differentiation capacity, goblet cell hyperplasia and an imbalance in the production of mucins, with increased MUC5AC and reduced MUC5B ( Figure 2 ) (4850)