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[89] indicated that 2M was increased in COPD patients and was correlated with lower pulmonary diffusing capacity values, increased alveolar wall/septal thickening (fibrosis changes), and higher expressions of TGF-1, Smad4, and a-SMA

In a warning letter, the FDA said Juul wrongly painted its e-cigarettes, known in the industry as ENDS, as safer than cigarettes and marketed them intentionally to young people