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First, as a narrative review, it does not follow a systematic review or meta-analytic methodology, which limits the ability to quantify effect sizes or establish causal relationships

Cigarette butt densities, expressed as cigarette butts per square metter, were reported directly in only 29.1% of the records, while 70.9% were indirectly estimated from articles that quantified total anthropogenic litter densities and the proportion of cigarette butts within them

The researchers estimated that 3 years after diagnosis, 75% of those who quit smoking would be alive, compared with 66% of those who continued smoking

The due date for comments from interested parties was extended to July