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Pharmaceutical-grade nicotine

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Regarding the pharmacokinetic effect of rs28379954, C allele carriers had an ~42% lower CLZ dose-adjusted serum concentration than TT genotype carriers in smokers ( p = 0.004), whereas the C allele-carrying nonsmokers had 33% lower CLZ dose-adjusted serum concentration ratio than the TT genotype carrying nonsmokers ( p = 0.031

Factors such as cigarette design, including length and tobacco blend, play a crucial role in nicotine delivery and yield