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The search terms for PubMed are shown below: (Parkinson Disease[mh] OR Parkinson*[tiab]) AND (Epigenomics[mh] OR epigenetics[tiab] OR DNA methyl* OR CpG Islands[mh] OR demethylat*[tiab] OR histone[tiab] OR non-coding RNA) AND (toxicant[tiab] OR solvent[tiab] OR environment[tiab] OR cigarette*[tiab] OR smoking[tiab] OR coffee[tiab] OR caffeine[tiab] OR pesticide[tiab] OR metal[tiab] OR air pollution OR contaminant[tiab] OR exposure[tiab] OR ibuprofen[tiab]) Exact search terms for other databases can be found in Supplementary S1

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