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While many do not include the chemical additives found in commercial brands, burning tobacco still produces harmful chemicals like tar, carbon monoxide, and carcinogens

Another 10L volume of spiking solution is added to a second 2 mL aliquot of the Laboratory Reagent Blank (LRB*) prior to solvent substitution and clean-up through the SPE cartridges to make the Laboratory Fortified Blank (LFB*)

Over the next decade, we anticipate a significant shift in the nicotine landscape whereby smoke-free products overtake combustibles to become the primary driver of industry growth. Cigarette consumption in the US has been declining steadily for decades, a trend Goldman Sachs expects to accelerate in the coming decade