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The pathophysiological mechanisms are believed to be interconnected between immune, inflammatory, neurotransmitter, genetic, and oxidative pathways (Pun et al., 2009

82 An 2013 study in the state of Queensland found a greater density of tobacco retailers, and that tobacco was sold in a greater variety of store types, in low socioeconomic areas

Although often perceived as safer than combustible cigarettes, mounting evidence confirms neurotoxic effects of nicotine in e-cig aerosols, and indicates that components other than nicotine can be detrimental to the developing brain

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