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Further information can be found at Use of E-Cigarettes Overall, 13.4% of adults in the local survey used e-cigarettes either daily (8.5%) or occasionally (4.8%)

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For our COVID-19 analyses, we used a two-sided of 0.0025 (based on comparing four COVID-19 outcomes and five substance use exposures) and for the other infectious disease outcomes, a threshold of 0.00071 (based on comparing 14 FinnGen infectious respiratory diseases and five substance use exposures) as a heuristic that allows for follow-up analyses for a plausible number of findings

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