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In addition, to facilitate regulatory acceptance, applicants should clearly describe their NAM, including the context in which the NAM will be used (e.g., for screening/prioritization or quantitative risk assessment), the relevance of the model system to human biology and mechanisms of toxicity, and how the NAM informs the toxicological issue/gap

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Some of them are chemically similar to substances known to trigger asthma through hypersensitivity reactions and may pose significant health risks

By combining prevention efforts, early intervention, and tailored support, individuals can find the strength and resources they need to overcome addiction and lead fulfilling, drug-free lives