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The difference between the total number of electronic nicotine delivery system applications made (26.64 million) and the various ways in which applications are resolved (refuse to accept, refuse to file, marketing denial order, marketing granted order, withdrawal by applicant, and closure) stood at 497,000 applications unaccounted for in March 2025

These NPM Adjustment Disputes were and are subject to a multi-state arbitration process under the MSA which became very time consuming, with the first arbitration completed in 2013 relating to the payment due in April 2004

The amended PACT Act extended that ban to vapes and other ENDS effective April 26, 2021

Brands like ICEBERG, Killa, and VELO offer reliable mid-to-high strength options