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The posterior cingulate cortex has also been shown to be deactivated by meditation, so Brewer hypothesized that this region would play a critical role in how mindfulness-based interventions app-based or otherwise affect the brain and change behaviors

Using the meta-regressionBayesian, regularized, trimmed (MR-BRT) tool, we estimated a pooled relative risk for each outcome that incorporated significant sources of systematic bias, within-study correlation, and between-study heterogeneity 18

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