is cigarette tobacco fermented Aging, Curing and Fermenting Cigar Tobacco Fermentation: The Beasts of

Stage Two: Genetic Alterations Carcinogenic substances such as nitrosamines, polycyclic aromatic hydrocarbons (PAHs), and formaldehyde cause mutations in oncogenes and tumor suppressors (e.g., p53) present in the DNA of the mouth's lining

9 NICOTINE ADDICTION Like all drug addictions, nicotine addiction is characterized by compulsive use, use despite harmful effects, pleasant effects, difficulty in quitting or controlling use, recurrent cravings, tolerance, physical dependence, and relapse following abstinence

Prasad GL, Jones BA, Chen P, et al

But researchers found this increase in health care costs dissipates within 3 months after quitting