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Americas FDA (Food and Drug Association) describes nicotine as a highly addictive chemical compound present in the Tobacco plant. It is a natural insecticide, but when ingested by humans it acts as both a stimulant and depressant - it stimulates areas of the brain that regulate processes that control our mood and cognition, as well as stimulating the production of hormones that reduce tiredness - but studies suggest that smaller doses encourage the sedative effect, reducing anxiety and anger

Note that the numbers in parentheses (1, 2, etc.) are clickable links to medically peer-reviewed studies

Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2020

[6] According to Wigand, he was subsequently harassed and received anonymous death threats