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In addition, as noted by Holder et al., 10 the much larger footprint of a cube design may be problematic in crowded spaces

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Samples were then extracted and cleaned according to AOAC Method 2007.01 for pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulphate (REFERENCE: available online at Statistical Analyses Statistical analyses were performed in R 37

Such a limitation is unavoidable: comparisons between different methods to estimate smoking-attributable mortality did not reveal a best-practice method [46, 47], and even if good estimates of smoking prevalence are available to potentially directly estimate smoking-attributable mortality, other factors like smoking intensity are often harder to measure and to take into account in direct estimates