tobacco free icon Do not smoke 3 | Free icon rainbow Substrate choices Free Cultivated tobacco (Nicotiana tabacum)

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The pleiotropic effects of tobacco smoke on the immunostimulatory function of DCs are further illustrated by a study reporting a diminished capacity of DCs from cigarette smoke-exposed mice to induce IL-2 production by T cells, which was associated with a decreased antigen-specific T-cell proliferation in vivo

PARN is a multifunctional enzyme that removes poly(A) tails from the 3' end of mRNAs, playing a key role in regulating mRNA stability and thus, the cell transcriptome and gene expression