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He led a clinical trial that found that adaptive pharmacotherapy, combined with behavioral counseling, improved chances of cessation compared with standard medication treatment

Its signature red and white packaging , bold tobacco flavor, and long-running marketing legacy have made it a cultural icon

This highlights the challenge of identifying and enforcing restrictions on concept-flavoured vapes, as it can be difficult to determine whether a concept-flavoured product meets the legal definition of a flavoured tobacco product from the name alone.34 Notably, a chemical analysis found that nearly all concept-flavoured tobacco products contained high concentrations of the same flavour chemicals found in explicit-flavoured products.35 Since many concept-flavoured vapes are thought to contain explicit flavours,36 this study likely underestimates violation rates in vape shops

Nicotine is a stimulant that affects the central nervous system, heart rate, and blood pressure