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All forms of tobacco use are harmful, and there is no safe level of exposure

Among people in this age group, 10.4 percent (or 4.0 million people) vaped nicotine, and 4.3 percent (or 1.7 million people) used tobacco products, including 3.0 percent (or 1.2 million people) who smoked cigarettes in the past month

Meanwhile, the content of total soluble sugar and reducing sugar was significantly increased, and the volatile aroma components, such as 3-hydroxy--damascone, 2,3-dihydro-3,5-dihydroxy-6-methyl-4 H-Pyran-4-one, ethyl palmitate, ethyl linolenic acid, etc., were significantly increased

For this reason, cotinine makes a useful biomarker in nicotine testing