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Early bronchiolitis obliterans symptoms include: Getting short of breath Difficulty exercising Fatigue Nose, mouth, and eye irritation Other respiratory diseases Wheezing Without treatment the disease gets progressively worse and in the long term can even lead to death if left unattended

On July 10, 1997, the Joe Camel campaign was retired and replaced with a somewhat more adult campaign which appealed to the desires of twenty-somethings to meet -- or be -- beautiful and exotic women (desires they nonetheless share with adolescent males) in 1930s attire and themes

The low heterogeneity observed in studies on current users (I 2 = 0%) suggests consistent results, while the moderate heterogeneity for former and ever users emphasizes the need for further research to explore the complexities of e-cigarette exposure and its role in COPD development

Given the popularity of e-cigarettes, there are many questions about the way they are regulated and their impacts on health