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Using a nicotine delivery system, other than smoking, cuts out many of the harmful effects of the smoke itself

5.3 Mitochondrial biogenesis in IPF Repeated damage to type II alveolar epithelial cells is an important cause of pulmonary fibrosis, but repeated damage to such cells is not necessary in the progression of pulmonary fibrosis (Larson-Casey et al., 2019)

It's just a full body sedative