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More specifically, the British National Formulary marks with bullet points potentially harmful drug pairs which should be prescribed cautiously, under appropriate monitoring, or avoided altogether (Drugs.com Drug Interaction Checker (DDIC) and DrugBank.com classify interactions into four severity levels: major, moderate, minor, and unknown (Knox et al., 2024

Lartey FM, Ahn GO, Shen B, Cord KT, Smith T, Chua JY et al (2014)